10 Days in Italy Itinerary (2025): The Perfect First-Timer’s Guide

Tim

by Tim | Last Updated September 2, 2025

10 Days in Italy Itinerary
Some of the links on that page are Affiliate Links As an Amazon Associate, we earn from qualifying purchases. We may receive a small commission at no extra cost to you.
Amazon and the Amazon logo are trademarks of Amazon.com, Inc. or its affiliates.

I’ll be honest – planning my first 10-day trip to Italy felt completely overwhelming. Between deciding which cities to prioritize, figuring out transportation, and choosing where to stay, it felt like every source I read gave me a different answer. Italy has so much to offer that it’s easy to feel lost in the options. Sound familiar?

But here’s what I discovered after spending those incredible 10 days exploring Italy: it’s actually the perfect amount of time for a first visit. Not too short that you’re constantly rushing, but not so long that you burn out or blow your entire travel budget.

Ten days in Italy gives you enough time to experience the country’s most iconic destinations while still having room to breathe, explore, and maybe even get a little lost (in the best possible way).

After visiting Italy multiple times and learning from my early mistakes, I’ve put together this complete guide based on what actually works. We’re talking about a realistic itinerary that covers the absolute must-sees – Rome’s ancient wonders, Florence’s Renaissance masterpieces, Venice’s magical canals, Milan’s sophisticated culture, and even the stunning beauty of Lake Como – without feeling like you need a vacation from your vacation.

This isn’t just another cookie-cutter itinerary you’ll find everywhere online. I’m sharing the real details: exactly how to get between cities, where to stay for the best experience, how much things actually cost, and those insider tips that make the difference between a good trip and an absolutely unforgettable one. Plus, I’ll give you alternative routes if the classic northern circuit isn’t quite your style.

Let’s dive into everything you need to know to plan an incredible 10 days in Italy itinerary.

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

Why Choose the 10 Days in Italy Itinerary?

10 Days in Italy Itinerary, Dorsoduro Quarter, Venice
Dorsoduro Quarter, Venice

Ten days in Italy hits that perfect sweet spot for first-time visitors – enough time to see the country’s most incredible highlights without feeling like you’re sprinting through train stations every single day. After doing shorter trips that left me feeling rushed and longer ones where I started getting travel fatigue, I can honestly say 10 days is the magic number.

What can you see in 10 days

With 10 days, you can comfortably explore four major destinations plus day trips. We’re talking 3 days in Rome to really soak up the ancient history and Vatican treasures, 2 days in Florence for Renaissance art and maybe a Tuscan wine tour, 2 days in Venice to experience the canals and nearby islands, plus time for Milan’s sophisticated culture and the breathtaking beauty of Lake Como.

You’ll get a genuine taste of different Italian regions – from the ancient south to the elegant north – without that horrible feeling of constantly packing and unpacking.

Is 10 Days in Italy Enough For a First Trip

Absolutely, and here’s why it works so well. You’ll have enough time in each city to move beyond just checking off tourist attractions and actually experience local life – lingering over long dinners, wandering through neighborhoods, maybe catching an evening aperitivo with locals.

But you won’t overstay anywhere and risk that “been there, done that” feeling. Ten days keep the excitement fresh while giving you enough experiences to understand why people fall head over heels for Italy.

The logistics work perfectly, too. Most international flights connect easily through Rome or Milan, the train system makes city-hopping incredibly smooth, and 10 days gives you flexibility for weather delays or those spontaneous moments when you discover an amazing little town and want to stick around for another espresso.

Plus, it’s long enough to justify the international flight costs but not so long that you’ll need to take a month off work or completely drain your savings account. Trust me, after those 10 days, you’ll either be planning your next Italy trip or seriously considering how to move there permanently.

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

How to Plan Your 10-day Italy Trip?

Pasta alla Carbonara with Truffles, Turin
Turin

Planning a 10-day Italy itinerary is all about getting three key things right: timing, transportation, and accommodation strategy.

Get these fundamentals sorted early, and the rest of your trip will flow beautifully. Mess them up, and you’ll spend your vacation fighting logistics instead of enjoying incredible pasta and Renaissance art.

Start with your flights and work backwards. I learned this the hard way after booking a beautiful Rome hotel only to realize my flight landed in Milan. Book your international flights first – ideally flying into Rome and out of Milan (or vice versa) to avoid backtracking.

This “open-jaw” approach saves you time and money, plus you end your trip in Milan, which has excellent international connections. If open-jaw flights are too expensive, a round-trip from Rome works fine; you’ll just add one extra train ride.

Book Train / Bus / Ferry / Flight

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

Book high-speed trains 2-4 weeks in advance. This is where you can save serious money or blow your budget. High-speed train tickets between major cities can literally double in price if you wait until the last minute. Rome to Florence, Florence to Venice, Venice to Milan – these routes are incredibly popular and fill up fast, especially during peak season. Use Omio, pick your times, and book those tickets early. Trust me on this one.

Choose accommodation strategically by city. Each Italian city has its own personality and ideal location strategy. In Rome, stay near Termini station or in Trastevere for easy access. Florence works best near Santa Maria Novella station or in the Oltrarno district. Venice is trickier – San Marco is central but expensive, while Cannaregio gives you a more authentic experience. Milan, you want to be near Centrale station or in the fashion district. For Lake Como, Bellagio or Varenna are your best bets for that postcard-perfect experience.


Plan your must-see attractions early. The Uffizi Gallery, Vatican Museums, and Leonardo’s Last Supper in Milan all require advance bookings – sometimes weeks ahead. Don’t be that person standing outside the Sistine Chapel, realizing you can’t get in. Book these major attractions when you book your flights, not when you arrive in Italy.

The beauty of 10 days is that you have enough time to be both organized and spontaneous. Plan the big stuff early, but leave room for those magical discoveries that make Italian travel so special.

Best Time for a 10 Day Italy Itinerary

10 Days in Italy Itinerary, Belluno, Dolomites
Belluno, Dolomites

After experiencing Italy in different seasons, I can tell you timing makes a huge difference in your experience – and your budget. The best time to visit Italy really depends on what you prioritize: perfect weather, smaller crowds, or saving money.

Spring (April-May) is absolutely magical. This is when Italy shows off – gorgeous weather, flowers blooming everywhere, and that perfect temperature where you can walk around all day without melting. The crowds haven’t hit summer madness levels yet, restaurant patios are open, and everything feels fresh and alive.

I did my first Italy trip in late April, and it was incredible. The only downside? Everyone else knows spring is amazing, so accommodation prices start climbing and popular attractions get busy.

Fall (September-October) might actually be my favorite time. The weather’s still fantastic, the summer crowds have gone home, and there’s this relaxed vibe everywhere. Plus, it’s harvest season in Tuscany, so if wine tours are on your list, this is your moment. Hotel prices drop from summer peaks, and locals are more relaxed after surviving tourist season. Early October especially hits that sweet spot of great weather and reasonable prices.

Summer (June-August) is peak everything – peak crowds, peak heat, peak prices, peak chaos. But here’s the thing: if summer is when you can travel, it’s still absolutely worth it. Italy in summer is vibrant and alive, with long days perfect for evening strolls and outdoor dining.

Just book everything way in advance, start your sightseeing early in the morning, take afternoon breaks during the heat, and embrace the Italian rhythm of life. Venice can be particularly swampy in July and August, fair warning.

Winter (November-March) is Italy’s best-kept secret. Sure, it’s cooler and some coastal stuff might be closed, but you’ll have major attractions practically to yourself, hotel prices are at their lowest, and there’s something really special about seeing Rome or Florence without crowds. Christmas markets in northern cities are beautiful, and if you hit a sunny winter day in Rome, it’s absolutely perfect. Just pack layers and be flexible with the weather.

Pro Tip

For a 10-day first trip, I’d personally go with late April-May or September-October. You get the best balance of weather, crowds, and costs, plus everything’s open and running a full schedule.

Get our FREE Italy
Travel Guide
E-Book

This printable guide is your ultimate companion for exploring Italy, with insider tips, detailed itineraries, transportation advice, must-see attractions, and more.

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

How to Get Around Italy Once You Get There

10 Days in Italy Itinerary, Greve in Chianti, Tuscany
Greve in Chianti, Tuscany

Honestly, Italy’s transportation system blew me away on my first trip – and I say this as someone who was terrified about navigating a foreign country where I barely spoke the language. Once you understand the basics, getting around Italy is incredibly easy and actually part of the fun.

High-speed trains are absolutely the way to go for this itinerary. Italy’s rail network is seriously impressive – Rome to Florence in 1.5 hours, Florence to Venice in 2 hours, Venice to Milan in 2.5 hours. These aren’t your typical slow European trains; we’re talking smooth, comfortable, fast trains that drop you right in city centers instead of some random airport 45 minutes outside town. I was doubtful at first, but after my first high-speed train ride, I was completely converted.

Book train tickets in advance through Trenitalia or Italo. There are two main companies – Trenitalia (the national railway) and Italo (private competitor). Both are reliable, but I usually go with whatever has better times or prices for my route. I personally use Omio because it compares both companies in one place and shows all available times and prices side by side, making it super easy to find the best options without checking multiple sites. All options give you English interfaces, let you choose your seats, and you just show the QR code on your phone. Super simple.

Book Train / Bus / Ferry / Flight

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

Regional trains are great for day trips – like Florence to Pisa, or exploring smaller Tuscan towns. They’re slower and less fancy than high-speed trains, but way cheaper and you don’t need advance reservations. Perfect for spontaneous side trips.

Car rental makes sense for specific situations. If you want to explore the Tuscan countryside, drive the scenic route around Lake Como, or really dig into wine regions at your own pace, a car gives you total freedom. But for city-to-city travel between Rome, Florence, Venice, and Milan? Skip the car. You’ll deal with traffic, expensive parking (€20-40/day in cities), and those sneaky ZTL restricted zones that hit tourists with hefty fines.

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

City transportation is straightforward. Rome has metros and buses, Florence is totally walkable, Venice uses water buses (vaporetti), and Milan has excellent metro and tram systems. Most cities offer day passes that cover public transport – usually worth it if you’re doing more than 2-3 rides.

The key is matching transportation to what you’re doing. Trains for main routes, local transport for cities, and car rental for one countryside segment if that’s your thing.

Best 10-day Italy Itinerary: Cities, Countryside & Lakes

10 Days in Italy Itinerary, Capri Coast
Capri Coast

This is the itinerary I wish I’d had on my first trip to Italy – it hits all the absolute must-sees while giving you enough time to actually enjoy each place instead of just checking boxes. We’re covering Italy’s greatest hits: ancient Rome, artistic Florence, magical Venice, sophisticated Milan, and stunning Lake Como, with built-in flexibility for day trips and spontaneous discoveries.

The route flows perfectly from south to north (or you can reverse it), with logical train connections and each destination offering a completely different slice of Italian culture. You’ll experience imperial history, Renaissance masterpieces, canal romance, fashion capital vibes, and alpine lake beauty – basically everything that makes people fall in love with Italy in the first place.

Day Destination Overnight
1–3 🇮🇹 Rome Rome
4–5 🇮🇹 Florence Florence
6–7 🇮🇹 Venice Venice
8 🇮🇹 Milan Milan
9 🇮🇹 Lake Como Lake Como
10 ✈ Departure Milan / Rome

Why this route works so well: You start with Rome’s incredible but intense energy, move to Florence’s more manageable Renaissance charm, experience Venice’s unique magic, then finish with Milan’s sophistication and Lake Como’s natural beauty. It’s like a perfectly curated introduction to everything Italy offers, and the pacing lets you actually absorb each place instead of just surviving it.

The train connections are smooth, each city offers different experiences, and you end on the relaxing high note of Lake Como before flying home. Trust me, this combination will give you enough amazing memories to last a lifetime – and probably enough inspiration to start planning your next Italy trip before you even get home.

Day 1–3: Rome – Ancient Wonders & Vatican City

10 Days in Italy Itinerary, Interior of St. Peter's Basilica
Interior of St. Peter’s Basilica

Rome absolutely blew my mind on my first visit – and honestly, it still does every time I go back. There’s something incredible about walking through a city where you’re literally surrounded by 2,000+ years of history, where ancient ruins sit next to bustling cafes and every corner reveals another incredible sight. Three days gives you enough time to see the major highlights without feeling completely overwhelmed by everything this incredible city has to offer.

Getting From The Airport to Rome

From Fiumicino (FCO): The Leonardo Express train is your best bet – €14, takes 32 minutes straight to Termini station, runs every 15 minutes. Way easier than dealing with taxis in Roman traffic, plus you’ll arrive right in the city center. If you’re staying near Trastevere or Vatican, regular FL1 trains make more stops and cost €8, taking about 45 minutes.

From Ciampino (CIA): This smaller airport mainly serves budget airlines. Take the Terravision or SitBusShuttle (€6) to Termini station – about 45 minutes depending on traffic. Taxis cost €30 fixed rate, which might be worth it if you have lots of luggage or arrive late at night.

Pro tip

I learned the hard way: Validate your train ticket in those little yellow machines before boarding, or you’ll get hit with a fine. The ticket inspectors don’t care that you’re a confused tourist – ask me how I know!

Things to Do in Rome

10 Days in Italy Itinerary, Roman Forum
Roman Forum

Must-see highlights: Colosseum, Roman Forum, Pantheon, Trevi Fountain, Spanish Steps

Day 1: Ancient Rome – Start early at the Colosseum (book skip-the-line tickets in advance, seriously). The underground level tour is absolutely worth the extra cost if you can swing it. Walk next door to the Roman Forum and Palatine Hill – this was basically ancient Rome’s downtown, and the views from Palatine over the whole area are incredible. End your day at the Pantheon (free entry!) – this 2,000-year-old temple with a hole in the roof still gives me chills.

Day 2: Vatican Museums & St. Peter’s Basilica – Another early start because these places get absolutely insane with crowds. The Vatican Museums are massive (we’re talking 9 miles of galleries), but the Sistine Chapel ceiling is genuinely one of the most beautiful things you’ll ever see. St. Peter’s Basilica is free but equally impressive – climb the dome if you’re not claustrophobic. The views over Rome are worth every one of those 551 steps.

Day 3: Neighborhoods & Hidden Gems – Hit the Trevi Fountain early morning for photos without crowds, then explore the Spanish Steps area. Spend your afternoon in Trastevere – this medieval neighborhood across the river feels like a different city entirely, with narrow cobblestone streets, ivy-covered buildings, and incredible restaurants. Perfect for wandering and getting lost.

Evening strolls in Trastevere – This is where Rome really comes alive at night. The whole area fills up with locals and travelers, restaurants spill onto the streets, and there’s this amazing energy that makes you never want to leave. Don’t miss Campo de’ Fiori for evening drinks and people-watching.

10 Days in Italy Itinerary, Rome
Rome

Where to Stay in Rome

Near Termini Station if you want easy train access for arriving and departing – tons of hotel options from budget to luxury, plus you can walk to most major sights or hop on the metro. The area’s improved a lot in recent years and it’s super convenient.

Trastevere if you want that authentic Roman neighborhood experience – charming medieval streets, amazing restaurants, and you’ll feel like you’re living like a local. Just know it gets pretty lively at night, which is awesome unless you’re an early sleeper.

Spanish Steps/Tridente area for luxury shopping and that classic Rome elegance – you’ll pay more, but you’re in the heart of everything beautiful about the city.


Day 4–5: Florence – Art, Architecture & Tuscany

10 Days in Italy Itinerary, Florence
Florence

Florence completely changed how I think about art and history. Coming from Rome’s grand scale and ancient chaos, Florence feels more intimate and manageable – but the artistic treasures here are absolutely mind-blowing. This is where the Renaissance basically started, and walking through the historic center feels like stepping into a living museum where every building tells an incredible story.

How to Get to Florence From Rome

High-speed train is absolutely the way to go – Frecciarossa or Italo trains take just 1.5 hours and arrive right in Florence’s city center at Santa Maria Novella station. Tickets cost €25-60 depending on when you book and what class you choose. I always book a few weeks ahead for better prices and guaranteed seats.

The journey itself is beautiful – you’ll pass through gorgeous Tuscan countryside with rolling hills, vineyards, and medieval hilltop towns. Grab a window seat on the left side for the best views. From Santa Maria Novella station, you can walk to most Florence attractions in 10-15 minutes, or it’s a quick taxi ride to your hotel.

Book Train / Bus / Ferry / Flight

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

Things to Do in Florence

10 Days in Italy Itinerary, Florence Cathedral Detail
Florence Cathedral Detail

Uffizi Gallery & Accademia (Michelangelo’s David) – These are the big two that absolutely require advance booking. The Uffizi houses the world’s best Renaissance art collection – Botticelli’s Birth of Venus, Leonardo da Vinci, Michelangelo. I spent 3 hours there and could have easily stayed longer. Book the earliest slot possible (8:15 AM) to avoid crowds and actually see the paintings without people constantly pushing past you.

The Accademia is smaller, but Michelangelo’s David alone is worth the visit – seeing it in person is completely different from photos. The statue is massive (17 feet tall) and the detail is incredible. Book these tickets 2-4 weeks ahead, especially during peak season.

Duomo & Ponte Vecchio – Florence’s cathedral with Brunelleschi’s famous dome is stunning, and climbing to the top gives you incredible views over the red rooftops and Tuscan hills beyond. The 463 steps are worth it, but book ahead because they limit numbers daily. The cathedral itself is free to enter, and the interior is beautiful, but the real highlight is that dome climb.

Ponte Vecchio, the famous bridge lined with jewelry shops, is beautiful especially at sunset – though it gets packed with tourists during the day. The bridge has been rebuilt multiple times but has had shops on it since the 13th century. For the best photos of the bridge, walk to Ponte Santa Trinita (the next bridge over).

Palazzo Pitti and Boboli Gardens – This massive Renaissance palace was home to the powerful Medici family and houses multiple museums. The gardens behind it are gorgeous and give you amazing views back over Florence. It’s a perfect afternoon escape when you need a break from crowded museums. The gardens are especially beautiful in spring when everything’s blooming.

10 Days in Italy Itinerary, San Lorenzo Leather Market
San Lorenzo Leather Market

San Lorenzo Market and Central Market – The leather market around San Lorenzo church is where you can bargain for leather goods (quality varies wildly, so inspect carefully). The Central Market upstairs has incredible food vendors – perfect for lunch or picking up Italian specialties to take home. The truffle pasta and fresh mozzarella stands are amazing.

Evening in Oltrarno neighborhood – Cross the river to where locals actually live and work. This area has amazing artisan workshops, antique shops, and authentic restaurants without the tourist crowds. Perfect for wandering and discovering hidden gems.

Check out the Oltrarno’s artisan workshops where you can watch craftspeople restoring furniture, making jewelry, or creating leather goods. The sunset views back toward the Duomo from here are incredible, especially from Piazzale Michelangelo.

Day trip to Chianti Wine Route or Pisa/Siena – Florence’s location makes it perfect for day trips. The Chianti wine region is gorgeous rolling hills covered in vineyards – you can join organized tours (€60-100) or rent a car for more flexibility. Towns like Greve in Chianti and Castellina are perfect for wine tasting and lunch.

Pisa is just 1 hour by train (€8-15) if you want that classic Leaning Tower photo – you can see the main sights in half a day and be back for dinner. Siena takes about 1.5 hours by bus and has one of Italy’s most beautiful medieval town squares (Piazza del Campo) where they hold the famous Palio horse race twice a year.

Driving/ZTL tips if you rent a car here – Florence has strict ZTL (limited traffic zones) in the historic center. If you drive into these areas without permission, you’ll get hit with €80+ fines that show up months later. Most rental cars aren’t allowed in the center anyway. If you rent a car for Tuscan day trips, pick it up outside the city center (many car rental companies have locations near the train station) and return it the same way. The countryside drives through Chianti are absolutely beautiful, but the roads can be narrow and winding.

🚗 Where to Park in Florence & Milan

Driving into Italy’s major cities can be tricky with ZTL zones and limited parking, but don’t worry — we’ve got you covered with detailed guides:

👉 Where to Park in Florence When Arriving by Car – Best garages, tips to avoid ZTL fines, and budget-friendly options just outside the center.

👉 Where to Park in Milan When Arriving by Car – Smart spots to leave your car, whether you’re heading to the Duomo, Navigli, or staying overnight.

Where to Stay in Florence

Santa Maria Novella area (near the train station) if you want easy transport connections and don’t mind being a 10-minute walk from the historic center. Tons of hotel options, and you can easily catch trains for day trips.

Historic Center for maximum convenience – you’ll be steps from the Duomo, Uffizi, and all major sights. More expensive but you can walk everywhere and really feel like you’re living in Renaissance Florence.

Oltrarno, if you want that authentic local experience – quieter streets, local restaurants, artisan workshops, and you’ll feel like you’re living alongside real Florentines instead of just tourists.


Day 6–7: Venice – Canals & Hidden Corners

San Lorenzo Leather Market, Venice
Venice

Venice is pure magic – there’s honestly no other place on Earth quite like it. After the Renaissance elegance of Florence, arriving in Venice feels like stepping into a completely different world where an entire city literally floats on water. It’s romantic, mysterious, and yes, sometimes overwhelmingly touristy, but there’s a reason people have been falling in love with this place for centuries.

How to Get to Venice From Florence

High-speed train takes about 2 hours – Frecciarossa or Italo trains run frequently throughout the day and cost €25-50 if you book ahead. The journey passes through beautiful countryside and you’ll arrive at Venezia Santa Lucia station, which sits right on the Grand Canal. Walking out of that train station and seeing the canal for the first time is honestly an incredible moment.

From the train station, you have two options: Take a vaporetto (water bus) to your accommodation – it’s slower but gives you that immediate Venice experience gliding down the Grand Canal. Or walk if you’re staying in certain areas like Cannaregio or San Marco – Venice is actually pretty compact, though you will get lost (and that’s half the fun). Wheeled luggage on Venice’s bridges is a nightmare, so pack light or be prepared for some arm workout.

What to Do in Venice in 2 Days

10 Days in Italy Itinerary, Doge's Palace, Venice
Doge’s Palace, Venice

St. Mark’s Basilica & Doge’s Palace – St. Mark’s Square is Venice’s heart and these two buildings are absolutely stunning. The basilica is free but often has long lines – go early morning or late afternoon. The golden mosaics inside are incredible, and climbing the bell tower gives you amazing views over the city and lagoon.

Doge’s Palace was the seat of Venice’s rulers, and it’s as lavish as you’d imagine. Through the famous Bridge of Sighs, it connects directly to the old prison — a chilling reminder of Venice’s darker history. Walking across it today gives you the same view prisoners once sighed over as they left freedom behind.

Gondola ride or Vaporetto on the Grand Canal – Yes, gondolas are expensive (€80 for 30 minutes), but honestly it’s magical, especially at sunset. If that’s too pricey, the vaporetto water buses give you similar canal views for just €7.50 per ride. The Grand Canal is Venice’s main “street” and riding along it feels like a moving tour of incredible palaces and bridges. The Rialto Bridge view is classic Venice photography.

Explore Burano and Murano islands – These islands are about 45 minutes by vaporetto and offer a nice break from Venice’s crowds. Murano is famous for glass-making – you can watch artisans blow glass and visit shops selling beautiful pieces. Burano has these incredible rainbow-colored houses that make for amazing photos, plus they’re famous for lace-making. Both islands have great seafood restaurants and a much more relaxed vibe than the main Venice.

Local cicchetti (Venetian tapas) experience – This is how Venetians actually eat and drink. Cicchetti bars serve small plates – think mini sandwiches, seafood bites, olives, cheese – paired with wine or spritz cocktails. Bar hopping for cicchetti is a fun evening activity and way more authentic than sitting in tourist restaurants around St. Mark’s. Try Cantina Do Spade or Al Mercà for the real experience.

10 Days in Italy Itinerary, St. Marks Basilica Venice
St. Marks Basilica Venice

Hidden Venice neighborhoods – Get lost in Cannaregio or Dorsoduro districts, where locals actually live. These areas have quiet canals, local bars, and way fewer tourists. Cannaregio has the old Jewish quarter with interesting history and great restaurants. Dorsoduro is the university area with art galleries and the beautiful Zattere waterfront, where locals walk and jog.

Venice photography tips I learned: Early morning (before 9 AM) and late evening (after 6 PM) are magic hours when the light is gorgeous and crowds thin out. St. Mark’s Square at sunrise is completely empty and absolutely beautiful. The side canals are often more photogenic than the famous spots – just wander and you’ll find incredible scenes.

Where to Stay in Venice

San Marco if you want to be in the absolute center of everything – you can walk to all major sights in minutes and you’re right in the heart of the action. Expect premium prices and crowds right outside your door, but the convenience and atmosphere are unbeatable, especially for a short stay.

Cannaregio for a more authentic Venetian experience – this is where locals actually live, and you’ll find better restaurants, quieter canals, and lower prices. Still totally walkable to major sights but you’ll feel like you’re experiencing real Venice instead of just tourist Venice.

Dorsoduro if you want that artsy, university neighborhood vibe – great restaurants, fewer tourists, and the beautiful Zattere waterfront for morning runs or evening walks. The Peggy Guggenheim Collection is here too if you’re into modern art.


Day 8: Milan – Fashion & History

10 Days in Italy Itinerary, Milan
Milan

Milan surprised me in the best way possible. Coming from Venice’s romantic canals, I expected Milan to be all business and no charm – but this city has incredible style, amazing food, and a sophisticated energy that’s totally different from anywhere else in Italy. One day is just enough to get a taste of what makes Milan special, from world-class art to that famous aperitivo culture.

How to Get From Venice to Milan

High-speed train takes 2.5 hours – Frecciarossa and Italo run frequently throughout the day, costing €30-70 depending on booking timing and class. The route passes through beautiful northern Italian countryside and you’ll arrive at Milano Centrale, one of Europe’s most impressive train stations. From Centrale, the metro gets you anywhere in the city quickly and efficiently.

Milano Centrale station itself is worth seeing – this 1930s architectural masterpiece looks more like a palace than a train station. Don’t rush out immediately; take a moment to appreciate the incredible ceiling and architecture.

Book Train / Bus / Ferry / Flight

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

What to Do in Milan in One Day

10 Days in Italy Itinerary, Galleria Vittorio Emanuele II
Galleria Vittorio Emanuele II

Duomo di Milano & Galleria Vittorio Emanuele II – Milan’s Gothic cathedral is absolutely stunning, and climbing up to the roof terraces to walk among the spires is one of Italy’s coolest experiences. Book tickets in advance because they limit numbers. The detail work on those spires up close is mind-blowing.

Right next to the Duomo, the Galleria is a beautiful 19th-century shopping arcade connecting to La Scala opera house – even if you’re not shopping, the architecture is gorgeous and it’s perfect for people-watching.

Leonardo’s Last Supper (book in advance) – This is probably the most famous painting in the world and seeing it in person is incredible. But here’s the catch: they only allow 25 people in for 15 minutes at a time, and tickets sell out months ahead. Book the moment you know you’re going to Milan. If you can’t get tickets, don’t stress – there’s plenty else to see.

Aperitivo in Navigli district – This is where Milan really comes alive in the evening. The Navigli canals (designed partly by Leonardo da Vinci) are lined with bars and restaurants. Aperitivo culture here is amazing – buy a drink and get access to incredible buffets of food. It’s like dinner and drinks combined, and the atmosphere is perfect for soaking up that sophisticated Milanese vibe.

Bonus if you have time: Sforza Castle houses several museums and Michelangelo’s last sculpture. The Brera district is perfect for wandering with its art galleries and boutiques. La Scala opera house offers tours if you’re into music history.

10 Days in Italy Itinerary, Galleria Vittorio Emanuele Glass Dome
Galleria Vittorio Emanuele Glass Dome

Where to Stay in Milan

Near Centrale station if you want easy train connections for arriving from Venice and departing to Lake Como. The area has improved dramatically, and you can reach the city center quickly by metro.

Fashion District/Centro Storico, if you want to be in the heart of Milan’s style and sophistication – walking distance to the Duomo, shopping, and best restaurants. You’ll pay more, but you’re in the middle of everything that makes Milan special.


Day 9: Lake Como – Italian Elegance by the Water

10 Days in Italy Itinerary, Varenna, Lake Como
Varenna, Lake Como

After all the city exploration, Lake Como feels like the perfect reward – stunning natural beauty, elegant villas, and that relaxed Italian lake lifestyle that makes you understand why celebrities choose to vacation here. The dramatic Alpine scenery reflected in crystal-clear water is absolutely breathtaking, and one day gives you a perfect taste of why this area is so beloved.

How to Get to Como From Milan

Regional train takes about 1 hour – trains run frequently from Milano Centrale to Como San Giovanni station, costing around €4-8. It’s one of the most scenic train rides you’ll take, passing through beautiful countryside as you approach the Alps. From Como station, it’s a short walk to the lake.

Alternatively, rent a car for maximum flexibility around the lake. The drive from Milan to Como takes about 1 hour and gives you complete freedom to explore different towns and villas at your own pace. The lakeside roads are gorgeous but can be narrow and winding.

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

What to See in Como

10 Days in Italy Itinerary, Menaggio, Lake Como
Menaggio, Lake Como

Scenic drive around the lake (Como → Bellagio → Varenna → Menaggio) – This is the classic Lake Como experience. Each town has its own personality: Como is the largest with great shopping and dining, Bellagio is the most famous with stunning villa gardens, Varenna is the most romantic with colorful houses cascading down to the water, and Menaggio offers incredible mountain views. The drive between towns is absolutely stunning.

Villa del Balbianello & Villa Carlotta – These historic villas with their incredible gardens are what Lake Como is famous for. Villa del Balbianello (accessible by boat or on foot) has appeared in movies like Star Wars and Casino Royale – the terraced gardens and lake views are incredible. Villa Carlotta has amazing botanical gardens and art collections. Both are worth visiting if you love gardens and history.

Boat crossings for quicker routes – The ferry system connects all the main towns and is actually faster than driving around the lake. Plus, seeing the villas and mountains from the water gives you a completely different perspective. A day pass costs around €15 and lets you hop on and off at different towns.

Como town exploration – Start with the cable car (funicolare) up to Brunate for panoramic views over the entire lake and Alps. Como’s historic center has beautiful architecture, great shopping, and excellent restaurants. The lakefront promenade is perfect for evening walks.

Where to Stay in Como

10 Days in Italy Itinerary, Bellagio, Lake Como
Bellagio, Lake Como

Bellagio for that classic Lake Como experience – this is the most famous town with incredible villa gardens and that postcard-perfect atmosphere. Expect higher prices but unbeatable location and charm.

Varenna for romance and authentic charm – colorful houses, quiet streets, and some of the most beautiful lake views. Less touristy than Bellagio but equally stunning.

Como town for practicality and transport connections – the largest town with the most dining and shopping options, plus easy train connections back to Milan for departure.


Day 10: Departure – Flexible Options

Your final day really depends on your flight schedule and energy level after nine amazing days exploring Italy. This is when having ended in northern Italy pays off – you’re perfectly positioned for easy departures while having some flexibility for last-minute experiences.

From Milan: shopping, final aperitivo – If you’re flying out of Milan Malpensa, you have time for some final shopping in the fashion capital. The Quadrilatero della Moda (fashion quadrilateral) is perfect for window shopping even if you’re not buying. Grab one last aperitivo in the Navigli district and soak up that sophisticated Milanese atmosphere before heading to the airport. The Malpensa Express train from Centrale takes 50 minutes and runs frequently.

From Rome: if you fly out here, return by high-speed train – Some travelers prefer to fly out of Rome due to better international connections. The high-speed train from Milan to Rome takes 3 hours, so factor this into your departure planning. You could even spend your final night back in Rome if you have an early morning flight.

Extend your stay option – If you’ve fallen in love with Lake Como (and honestly, who wouldn’t?), consider extending your trip by a day or two. The area has incredible hiking, more villa gardens to explore, and that relaxed pace that’s the perfect antidote to busy city sightseeing.

Get our FREE Italy
Travel Guide
E-Book

This printable guide is your ultimate companion for exploring Italy, with insider tips, detailed itineraries, transportation advice, must-see attractions, and more.

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

Practical Tips for 10 Days in Italy

Should you rent a car or rely on trains? For this classic itinerary, trains are definitely the way to go for city-to-city travel. Italy’s high-speed rail network is excellent, drops you in city centers, and saves you from dealing with traffic and parking nightmares. Consider renting a car only for specific segments like exploring Tuscany’s countryside or driving around Lake Como – then return it before continuing by train.

How to save money on tickets & transport – Book high-speed trains 2-4 weeks in advance for significant savings. For attractions, look into city tourism cards that bundle multiple sites – they’re not always cheaper but can save time on lines. Book major attractions (Uffizi, Vatican, Last Supper) as early as possible.

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

Luggage & packing tips – Pack light and bring wheels that work well on cobblestones. Italian train stations have lots of stairs and broken escalators. One carry-on size bag per person maximum. Leave room for purchases – you’ll want to bring home Italian leather, wine, or art. Consider shipping larger purchases home rather than struggling with extra luggage.

Italy ZTL zones explained – Most historic city centers have ZTL (Zona a Traffico Limitato) restricted zones where only authorized vehicles can enter. Driving into these areas without permission results in hefty fines (€80-200) that arrive months later. If you rent a car, ask your accommodation about parking outside ZTL zones or use Park & Ride facilities on city outskirts. GPS systems don’t always warn about ZTL zones, so research before driving in any Italian city center.

🚗 Lessons From the Road: What I Learned Driving Across Italy

My road trip through Italy really came alive the day I left Florence and headed into the Tuscan countryside. The train might get you between cities, but nothing compares to the freedom of a car when you’re winding through rolling vineyards, cypress-lined backroads, and medieval hill towns. Siena, San Gimignano, and tiny villages you’d never find on a rail map became spontaneous stops.

I pulled over at vineyards for tastings, lingered at roadside farmhouses selling olive oil, and watched the sunset from a quiet ridge without worrying about train schedules. That’s when I realized: Tuscany isn’t just about the destination — it’s about the slow, scenic drives in between.

Later in the trip, I swapped the Tuscan hills for the dramatic beauty of Northern Italy. Driving from Milan to Lake Como turned out to be one of the most breathtaking short routes of the journey. A train could have taken me there in under an hour, sure — but the magic was in the drive itself.

Passing through charming Lombardy towns, curving roads that hugged the mountains, and then suddenly catching the first glimpse of Como’s shimmering waters between the peaks — it felt like stepping straight into a postcard.

With a car, I didn’t just “arrive” in Como, I discovered hidden lakeside villages, stopped for lunch in Bellagio, and took the slower, scenic road that most visitors miss.

Not every drive was carefree, though. I still remember the stress of accidentally entering a ZTL zone in Florence and the relief of knowing I’d chosen the right rental car for mountain roads versus city streets. Those lessons taught me that planning ahead makes all the difference when driving in Italy.

If you’re planning your own trip, check out these guides:

👉 Tuscany Scenic Drives – Rolling hills, vineyards, and Renaissance towns.

👉 Milan to Lake Como by Car – One of the most scenic short drives in Northern Italy.

👉 Best Car for an Italy Road Trip – Compact vs. SUV, fuel efficiency vs. comfort.

👉 Driving in Italy: Rules & Tips – What every first-time driver should know.

👉 How to Avoid ZTL Zones in Italy – Save yourself stress (and fines).

Alternative 10 Day Itineraries

Southern Italy 10 Day Itinerary: Naples, Amalfi Coast, Capri, Pompeii

10 Days in Italy Itinerary, Pompeii, Near Naples
Pompeii, Near Naples

If the classic northern route doesn’t appeal to you, southern Italy offers completely different experiences. Start in Naples for incredible pizza and authentic southern Italian culture, spend time on the dramatic Amalfi Coast with its clifftop towns and stunning coastal drives, take a day trip to glamorous Capri Island, and explore the remarkably preserved ancient city of Pompeii. This route is more relaxed, coastal-focused, and gives you that Mediterranean vibe that’s totally different from the art-focused northern cities.

Sample Southern Route:

Day Destination Overnight
1–2 🇮🇹 Rome – 🏛 Colosseum, ⛪ Vatican, 🎭 Piazza Navona Rome
3–4 🍕 Naples – 🍕 Pizza, 🏛 Archaeological Museum, 🌋 Mt. Vesuvius views Naples
5–7 🌊 Amalfi Coast (Positano/Amalfi) – 🌅 Coastal drives, 🏖 Beaches, 🍋 Lemon groves Amalfi Coast
8 ⛵ Capri – 🌺 Gardens of Augustus, 🏞 Blue Grotto Capri
9 🏛 Pompeii Day Trip – ⛪ Ruins, 🏺 Ancient streets Naples
10 ✈ Return to Rome – 🛍 Last shopping, 🍝 Farewell dinner Rome

This works best April through October when the weather is perfect for coastal activities and everything’s open.

Transportation for Southern Route: Take the high-speed train from Rome to Naples (1.5 hours). From Naples, buses run to Amalfi Coast towns (SITA buses, 1.5-2 hours to Positano/Amalfi). Alternatively, rent a car in Naples for flexibility around the coast – the coastal drive is stunning but roads are narrow and parking is challenging. Ferries connect Amalfi Coast to Capri (45 minutes). Pompeii is easily reached by train from Naples (30 minutes on Circumvesuviana line).

🌊 Driving the Amalfi Coast: Road Trips & Travel Tips

Few drives in the world compare to the Amalfi Coast — narrow cliffside roads, pastel villages clinging to the rocks, and endless Mediterranean views. Before you hit the road, check out these must-read guides:

👉 Driving the Amalfi Coast: What You Need to Know – Rules, challenges, and tips for tackling Italy’s most famous coastal drive.

👉 Amalfi Coast Road Trip Itinerary (2025 Guide) – A step-by-step coastal route with must-stop towns.

👉 Rome to Amalfi Coast Drive You’ll Never Forget – The scenic way to reach Amalfi from Rome.

👉 Amalfi Coast 7-Day Itinerary – Perfect for travelers who want a full week along the coast.

Northern Italy 10 Day Itinerary: Dolomites, Verona, Turin, Lake Garda 

10 Days in Italy Itinerary, Verona
Verona

Northern Italy in 10 Days circuit is perfect for mountain lovers and those wanting to explore Italy’s Alpine region. This route offers dramatic mountain scenery, romantic medieval cities, sophisticated Piedmont culture, and stunning lake beauty. Perfect for hiking enthusiasts, wine lovers, and anyone wanting to see a different side of Italy beyond the usual tourist trail.

Sample Northern Route:

Day Destination Overnight
1–2 🇮🇹 Milan – ⛪ Duomo, 🛍 Galleria Vittorio Emanuele II Milan
3–5 🏔 Dolomites (Bolzano / Cortina) – 🚡 Cable cars, ❄ Scenic passes Dolomites
6–7 🍷 Verona – 🏛 Arena, 💕 Juliet’s Balcony Verona
8–9 ⛵ Lake Garda (Sirmione / Riva) – 🏖 Lakeside promenades, 🌸 Gardens Lake Garda
10 🏰 Turin – 🍫 Chocolate, 🚗 Fiat Museum Turin
11 ✈ Milan Departure

Best from June through September for mountain access, though Lake Garda and cities are beautiful year-round.


Transportation for Northern Route: From Milan, take trains to Bolzano (3.5 hours), then local buses to Dolomites towns. Rent a car for maximum Dolomites flexibility – the mountain drives are spectacular. Train from Bolzano to Verona (2.5 hours). Lake Garda is best explored by car or local buses from Verona (1 hour). Turin is 2 hours by train from Milan, perfect for a final day before departure.

🏔️ Driving in the Dolomites: Scenic Routes & Essential Guides

Exploring the Dolomites by car is one of the most breathtaking experiences in Italy — alpine passes, dramatic peaks, and hidden valleys you’ll never forget. Make sure you’re ready with these detailed guides:

👉 Dolomites Driving Guide: Scenic Routes & Safety Tips – Best mountain roads, maps, and tips for safe driving.

👉 Best Scenic Drives in Northern Italy (Dolomites & Beyond) – Handpicked routes to lakes, passes, and panoramic spots.

👉 Dolomites Via Ferrata Guide – Combine your road trip with thrilling via ferrata climbs.

👉 Best Cortina d’Ampezzo Hotels for a Dolomites Road Trip – Where to stay in the heart of the mountains.

Food & Wine Lovers Itinerary

10 Days in Italy Itinerary, Bologna
Bologna

This route focuses on Italy’s incredible culinary regions, from Emilia-Romagna’s pasta and Parmigiano production to Piedmont’s world-class wines and truffle culture. Perfect for travelers who want to experience authentic Italian food culture, cooking classes, wine tastings, and meeting local producers.

Sample Food & Wine Route:

Day Destination Overnight
1–2 🇮🇹 Rome – 🏛 Colosseum, 🍝 local trattorias, 🍷 aperitivo evenings Rome
3–4 🍝 Bologna – Pasta capital, 🧀 Parmigiano Reggiano tours Bologna
5 🥂 Modena – Traditional balsamic vinegar tasting Modena
6–8 🍇 Alba / Piedmont – Barolo & Barbaresco wine tastings, 🍄 Truffle hunting Alba / Piedmont
9 🌻 Tuscany (Chianti) – Vineyard tours & 👩‍🍳 cooking class Chianti Region
10 ✈ Return to Rome – Farewell dinner & departure Rome

This route works well from September through November for the harvest season and truffle season.

Transportation for Food & Wine Route: High-speed trains connect Rome to Bologna (2.5 hours). Bologna to Modena by regional train (45 minutes). Rent a car in Modena for exploring Piedmont wine regions around Alba – public transport is limited in the countryside areas. A car is essential for Chianti wine tours departing from a Florence base. Return the car in Florence and take a high-speed train back to Rome (1.5 hours).

10 Days in Italy Itinerary, Pasta alla Carbonara with Truffles
Pasta alla Carbonara with Truffles

Transportation Tips for All Alternative Routes

  • Car rental is most flexible for countryside and mountain regions, but adds costs (€30-60/day plus fuel, tolls, parking)
  • Regional trains work well for city connections, but are slower than high-speed options
  • Local buses serve coastal and mountain areas, but require more planning and patience
  • Ferry connections link islands and coastal towns, especially useful for Amalfi Coast and Lake Garda
  • Book accommodation early for Dolomites (limited options) and Amalfi Coast (high demand)

FAQs About 10 Days in Italy

What’s the best way to get around Italy in 10 days?

High-speed trains are the most efficient for traveling between Rome, Florence, Venice, and Milan. For Tuscany or Lake Como day trips, renting a car gives more flexibility.

How much does a 10 day trip to Italy cost?

A 10-day Italy trip typically costs €1,500–€3,000 per person, depending on travel style. Budget travelers can spend less with guesthouses and trains, while luxury stays and tours increase the cost.

Can you do Amalfi Coast in this itinerary?

Yes, but it requires swapping Lake Como or Milan for Naples and the Amalfi Coast. For first-time visitors, the Rome–Florence–Venice route is easier and less rushed.

Is 10 days enough to see Rome, Florence, and Venice?

Yes, 10 days is ideal for Italy’s “big three.” Spend 3 days in Rome, 2 in Florence with a Tuscan day trip, and 2 in Venice, plus travel days.

Do you need an International Driving Permit in Italy?

Yes, non-EU visitors must carry an International Driving Permit (IDP) with their home license. Car rental agencies often ask for it, and driving without one can result in fines.

Get our FREE Italy
Travel Guide
E-Book

This printable guide is your ultimate companion for exploring Italy, with insider tips, detailed itineraries, transportation advice, must-see attractions, and more.

10 Days in Italy Itinerary, Why Choose the 10 Days in Italy Itinerary?, What can you see in 10 days, Is 10 Days in Italy Enough For a First Trip, How to Plan Your 10-day Italy Trip?, Best Time for a 10 Day Italy Itinerary, How to Get Around Italy Once You Get There, Best 10-day Italy itinerary, Day 1–3: Rome – Ancient Wonders & Vatican City, Getting From The Airport to Rome, Things to Do in Rome, Where to Stay in Rome, How to Get to Florence From Rome, Things to Do in Florence, Where to Stay in Florence, Day 6–7: Venice – Canals & Hidden Corners, How to Get to Venice From Florence, What to Do in Venice in 2 Days, Where to Stay in Venice, Day 8: Milan – Fashion & History, How to Get From Venice to Milan, What to Do in Milan in One Day, Where to Stay in Milan, Day 9: Lake Como – Italian Elegance by the Water, How to Get to Como From Milan, What to See in Como, Where to Stay in Como, Day 10: Departure – Flexible Options, Practical Tips for 10 Days in Italy, Alternative 10 Day Itineraries, Southern Italy 10 Day Itinerary, Northern Italy 10 Day Itinerary, Food & Wine Lovers Itinerary, Transportation Tips for All Alternative Routes

💬 We’d love to hear from you!

Have questions, tips, or personal travel stories to share? Drop them in the comments below — your insights help fellow travelers plan their adventures too.

guest
0 Comments
Most Voted
Newest Oldest
Inline Feedbacks
View all comments

More Articles

  • Things to Do in Milan
    By Abu | Updated September 10, 2025

    Things to Do in Milan (2025): Complete Guide to Italy’s Fashion Capital

  • 3 Days in Milan Itinerary
    By Asia A. | Updated September 9, 2025

    3 Days in Milan Itinerary (2025): How to Spend the Perfect 72 Hours

  • 2 Days in Milan Itinerary
    By Luca | Updated September 9, 2025

    2 Days in Milan Itinerary (2025): The Perfect First-Timer’s Guide

  • 1 Day in Milan Itinerary
    By Abu | Updated September 7, 2025

    1 Day in Milan Itinerary (2025): How to See the Best of the City in 24 Hours

  • Milan Travel Guide
    By Asia A. | Updated September 8, 2025

    Ultimate Travel Guide to Milan (2025): Itineraries, Food, Neighborhoods & Insider Tips

  • Hidden Gem Cities in Italy
    By Abu | Updated September 5, 2025

    11 Hidden Gem Cities in Italy (2025): Underrated Italian Destinations Worth Visiting

  • Cheapest Cities to Visit in Italy
    By Mary | Updated August 30, 2025

    10 Cheapest Cities to Visit in Italy (2025): Budget Travel Guide 

  • Best Lakes in Italy
    By Luca | Updated August 30, 2025

    10 Best Lakes in Italy: Stunning Lake Destinations Worth Visiting

  • Best Cities to Visit in Italy
    By Tim | Updated September 5, 2025

    Best Cities to Visit in Italy (2025): Top 10 Italian Cities for Every Traveler